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1

Allosteric Regulation of Binding and Function at GCPRS

Nigel J.M. Birdsall, Christopher Browning, Jonathan Hern, Sebastian Lazareno

Journal:

Medicinal Chemistry Research

Year:

2004

File:

PDF, 441 KB

2004

2

Towards a high-affinity allosteric enhancer at muscarinic M1receptors

Sebastian Lazareno, Angela Popham, Nigel J. M. Birdsall

Journal:

Journal of Molecular Neuroscience

Year:

2002

Language:

english

File:

PDF, 81 KB

english, 2002

3

To What Extent Can Binding Studies Allow the Quantification of Affinity and Efficacy?

NIGEL J. M. BIRDSALL, SEBASTIAN LAZARENO

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 443 KB

english, 1997

4

Progress toward a high-affinity allosteric enhancer at muscarinic M1receptors

Sebastian Lazareno, Angela Popham, Nigel J. M. Birdsall

Journal:

Journal of Molecular Neuroscience

Year:

2003

Language:

english

File:

PDF, 68 KB

english, 2003

5

Substituted Pentacyclic Carbazolones as Novel Muscarinic Allosteric Agents: Synthesis and Structure−Affinity and Cooperativity Relationships

Gharagozloo, Parviz, Lazareno, Sebastian, Miyauchi, Masao, Popham, Angela, Birdsall, Nigel J. M.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 195 KB

english, 2002

6

Muscarinic interactions of bisindolylmaleimide analogues

Sebastian Lazareno, Angela Popham, Nigel J.M. Birdsall

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 114 KB

english, 1998

7

The effects of saponin on the binding and functional properties of the human adenosine A1 receptor

Fiona R. Cohen, Sebastian Lazareno, Nigel J.M. Birdsall

Journal:

British Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.63 MB

english, 1996

8

Selective labelling of dopamine (D2) receptors in rat striatum by [3H]domperidone but not by [3H]spiperone

Sebastian Lazareno, Stefano R. Nahorski

Journal:

European Journal of Pharmacology

Year:

1982

Language:

english

File:

PDF, 822 KB

english, 1982

9

The affinity of adenosine for the high- and low-affinity states of the human adenosine A1 receptor

Fiona R. Cohen, Sebastian Lazareno, Nigel J.M. Birdsall

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 391 KB

english, 1996

10

Multiple allosteric sites on muscarinic receptors

Nigel J.M. Birdsall, Sebastian Lazareno, Angela Popham, Jose Saldanha

Journal:

Year:

2001

Language:

english

File:

PDF, 83 KB

english, 2001

11

Selective allosteric enhancement of the binding and actions of acetylcholine at muscarinic receptor subtypes

Nigel J.M. Birdsall, Tim Farries, Parviz Gharagozloo, Shinsaku Kobayashi, Donald Kuonen, Sebastian Lazareno, Angela Popham, Masahiko Sugimoto

Journal:

Year:

1997

Language:

english

File:

PDF, 470 KB

english, 1997

12

Reply: effect of radioligand contamination on the analysis of homologous competition experiments

Sebastian Lazareno, Nigel J.M. Birdsall

Journal:

Trends in Pharmacological Sciences

Year:

2000

Language:

english

File:

PDF, 44 KB

english, 2000

13

Quantitation of allosteric interaction: The equilibrium potency of allosteric agents may differ from their potency in dissociation assays

Sebastian Lazareno, Nigel Birdsall

Journal:

Trends in Pharmacological Sciences

Year:

1996

Language:

english

File:

PDF, 141 KB

english, 1996

14

Effects of contamination on radioligand binding parameters

Sebastian Lazareno, Nigel J.M. Birdsall

Journal:

Trends in Pharmacological Sciences

Year:

2000

Language:

english

File:

PDF, 142 KB

english, 2000

15

Differential effects of selective and non-selective neuroleptics on intracellular and extracellular cyclic AMP accumulation in rat striatal slices

Sebastian Lazareno, Deborah B. Marriott, Stefan R. Nahorski

Journal:

Year:

1985

Language:

english

File:

PDF, 619 KB

english, 1985

16

Allosteric Interactions of Quaternary Strychnine and Brucine Derivatives with Muscarinic Acetylcholine Receptors

Gharagozloo, Parviz, Lazareno, Sebastian, Popham, Angela, Birdsall, Nigel J. M.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 83 KB

english, 1999

17

QUANTIFICATION OF RECEPTOR INTERACTIONS USING BINDING METHODS

Lazareno, Sebastian

Journal:

Journal of Receptor and Signal Transduction Research

Year:

2001

Language:

english

File:

PDF, 311 KB

english, 2001

18

Formation and Dissociation of M₁ Muscarinic Receptor Dimers Seen by Total Internal Reflection Fluorescence Imaging of Single Molecules

Jonathan A. Hern, Asma H. Baig, Gregory I. Mashanov, Berry Birdsall, John E. T. Corrie, Sebastian Lazareno, Justin E. Molloy, Nigel J. M. Birdsall and Brian K. Kobilka

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.71 MB

english, 2010

19

Cholinergic treatments for Alzheimer's disease

ROBERTS, FIONA, LAZARENO, SEBASTIAN

Journal:

Biochemical Society Transactions

Year:

1989

Language:

english

File:

PDF, 501 KB

english, 1989

20

Allosteric Interactions of Staurosporine and Other Indolocarbazoles with N -[ methyl - 3 H]Scopolamine and Acetylcholine at Muscarinic Receptor Subtypes: Identification of a Second Allosteric Site

Lazareno, Sebastian, Popham, Angela, Birdsall, Nigel J. M.

Journal:

Molecular Pharmacology

Year:

2000

Language:

english

File:

PDF, 254 KB

english, 2000